Phase 1, placebo-controlled, dose escalation trial of chicory root extract in patients with osteoarthritis of the hip or knee.
- 2010-07-09
- RCT · n = 40
- BMC musculoskeletal disorders 11(1)
- Nancy J Olsen
- Valerie K Branch
- Geetha Jonnala
- Mira Seskar
- Melisa Cooper
- PubMed: 20618964
- DOI: 10.1186/1471-2474-11-156
- High evidence
- Clinical
Efficacy evaluations at baseline and final visits included self-assessment questionnaires and measurement of the 25-foot walking time.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- 600 mg/day, 1200 mg/day, 1800 mg/day (three cohorts)