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Evidence-Based Supplement Research
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Cinnamon and Reduced Blood Cholesterol

Research synthesisModerate evidenceMixed effect size4 studies · 3 beneficial · 1 neutral · 0 harmful

Across 4 studies, 3 reported beneficial effects of cinnamon supplementation on blood cholesterol, with effect sizes ranging from moderate to large. The most robust evidence comes from a 2025 meta-analysis of 3,054 adults with type 2 diabetes showing moderate reductions in total cholesterol (WMD: -13.39 mg/dL). Effects were typically observed at doses of 600 mg to ≤2 g/day over 4–12 weeks.

  • Effective dose range: 600 mg–2 g/day
  • Studied populations: adults and the elderly with type 2 diabetes, patients with dyslipidemia

Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Evidence base is small (only 4 studies) — conclusions should be considered preliminary. One RCT (n=30) reported very large reductions (cholesterol decrease of 44.8 mg/dL), which may be an outlier and inflate the apparent effect size.

Generated Jul 15, 2026
Doses used in studies
  • mg/day: 600 (median 600, IQR 600–600) — 1 study
Time to effect
Median: 8.1 weeks · IQR 6.2 weeks–10.1 weeks · Range 4.3 weeks–2.8 months — Reported in 2 of 4 studies
4 of 4 papers
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