Skip to main content

Evidence-Based Supplement Research

Evidence-Based Supplement Research

Cissus quadrangularis and Reduced Energy Intake

Doses used in studies

mg/day: 300 (median 300, IQR 300–300) — 1 study

Time to effect

Median: 3.7 months · IQR 3.7 months–3.7 months · Range 3.7 months–3.7 months — Reported in 1 of 1 study

1 of 1 paper

Effects of Dichrostachys glomerata and Cissus quadrangularis Extracts on GLP-1 Secretion and DPP-4 Activity in Overweight and Obese Individuals: A Randomized Controlled Trial.
- 2025-12-25
- RCT · n = 248
- Medicina (Kaunas, Lithuania) 62(1)
- - Janvier Youovop
  - Guy Takuissu
  - Régine Minoue
  - Felix Nwang
  - Maryam Adegboyega
  - Crista Arrey
  - Inelle Makamwe
  - Julius Oben
- PubMed: 41597327
- DOI: 10.3390/medicina62010041
8 Insights on
- Reduced Energy Intake
- High evidence
- Large Human Trial
- Adults
energy intake (-16.2% and -17.5%)
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
300 mg/day