cocoa and Increased Platelet Count

Doses used in studies

g/day: 30 (median 30, IQR 30–30) — 1 study

Time to effect

Median: 7 days · IQR 7 days–7 days · Range 7 days–7 days — Reported in 1 of 1 study

1 of 1 paper

Effect of cocoa (Theobroma cacao L.) on platelet function testing profiles in patients with coronary artery disease: ECLAIR pilot study.

2022-09
Clinical Trial · n = 20
Open heart 9(2)
- Naveen Anand Seecheran
- Darin Sukha
- Kathryn Grimaldos
- Gabriella Grimaldos
- Srivane Richard
- Aleena Ishmael
- Ceylon Gomes
- Lirmala Kampradi
- Rajeev Seecheran
- Valmiki Seecheran
- Lakshmipathi Peram
- Darren Dookeeram
- Stanley Giddings
- Sherry Sandy
- Anil Ramlackhansingh
- Sadi Raza
- Pathmanathan Umaharan
- Antonio Tello-Montoliu
- David Schneider

PubMed: 36100318
DOI: 10.1136/openhrt-2022-002066

2 Insights on

Increased Platelet Count

Moderate evidence
Clinical

Cocoa augmented the inhibitory effect of clopidogrel, demonstrated by a reduction of 11.9% (95% CI 5.7% to 18.0%, p value 0.001), significantly decreasing the PRU by 26.85 (95% CI 12.22 to 41.48, p value 0.001).

Effect: Beneficial
Effect size: Small
Significant: Yes
Dose: 30 g/day of 65% cocoa (dark chocolate)