Prevention of covid-19 and other acute respiratory infections with cod liver oil supplementation, a low dose vitamin D supplement: quadruple blinded, randomised placebo controlled trial.
- 2022-09-07
- RCT · n = 601
- BMJ (Clinical research ed.) 378
- Sonja H Brunvoll
- Anders B Nygaard
- Merete Ellingjord-Dale
- Petter Holland
- Mette Stausland Istre
- Karl Trygve Kalleberg
- Camilla L Søraas
- Kirsten B Holven
- Stine M Ulven
- Anette Hjartåker
- Trond Haider
- Fridtjof Lund-Johansen
- John Arne Dahl
- Haakon E Meyer
- Arne Søraas
- PubMed: 36215222
- DOI: 10.1136/bmj-2022-071245
- High evidence
- Large Human Trial
- Mixed
227 (1.31%) participants in the cod liver oil group and 228 (1.32%) participants in the placebo group had a positive SARS-CoV-2 test result (relative risk 1.00, multiple comparison adjusted confidence interval 0.82 to 1.22).
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- 5 mL/day (10 µg vitamin D)