Echinacea for treating the common cold: a randomized trial.
- 2010-12-21
- RCT · n = 719
- Annals of internal medicine 153(12)
- Bruce Barrett
- Roger Brown
- Dave Rakel
- Marlon Mundt
- Kerry Bone
- Shari Barlow
- Tola Ewers
- PubMed: 21173411
- DOI: 10.7326/0003-4819-153-12-201012210-00003
- High evidence
- Large Human Trial
- Rigorous Journal
- Clinical
Mean illness duration in the blinded and unblinded echinacea groups was 6.34 and 6.76 days, respectively, compared with 6.87 days in the blinded placebo group and 7.03 days in the no-pill group. A comparison of the blinded groups showed a nonsignificant 0.53-day (CI, -1.25 to 0.19 days) benefit (P = 0.075).
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- equivalent of 10.2 g of dried echinacea root during the first 24 hours and 5.1 g during each of the next 4 days