Echinacea for treating the common cold: a randomized trial.
- 2010-12-21
- RCT · n = 719
- Annals of internal medicine 153(12)
- Bruce Barrett
- Roger Brown
- Dave Rakel
- Marlon Mundt
- Kerry Bone
- Shari Barlow
- Tola Ewers
- PubMed: 21173411
- DOI: 10.7326/0003-4819-153-12-201012210-00003
- High evidence
- Large Human Trial
- Rigorous Journal
- Clinical
Mean global severity was 236 and 258 for the blinded and unblinded echinacea groups, respectively; 264 for the blinded placebo group; and 286 for the no-pill group. A comparison of the 2 blinded groups showed a 28-point trend (95% CI, -69 to 13 points) toward benefit for echinacea (P = 0.089).
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- equivalent of 10.2 g of dried echinacea root during the first 24 hours and 5.1 g during each of the next 4 days