Randomized Trial of Milk Oral Immunotherapy: Fixed Low-Dose vs Escalation to Medium-Dose.
- 2026-04
- RCT · n = 32
- The journal of allergy and clinical immunology. In practice 14(4)
- Ken-Ichi Nagakura
- Kyohei Takahashi
- Yoko Miura
- Kaito Goto
- Akira Kawai
- Naoko Fusayasu
- Kiyotake Ogura
- Sakura Sato
- Motohiro Ebisawa
- Noriyuki Yanagida
- PubMed: 41633410
- DOI: 10.1016/j.jaip.2026.01.025
- High evidence
- Clinical
The rates of achieving 25 mL short-term unresponsiveness were 31% and 28% at 1 year and 47% and 44% at 2 years, respectively (P > .99).
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- 3-mL target (99-mg protein) or 25-mL target (825-mg protein)