Bedtime snacking and glycemic deterioration in young children with Type 1 diabetes on multiple daily injections: a randomized controlled crossover trial.
- 2025-11-21
- RCT · n = 28
- Nutrition & diabetes 15(1)
- Tuğba Gökçe
- Kağan Ege Karakuş
- Gül Yeşiltepe Mutlu
- Serra Muradoğlu
- Elif Eviz
- Ecem Can
- Carmel Smart
- Şükrü Hatun
- Hülya Gökmen Özel
- PubMed: 41271622
- DOI: 10.1038/s41387-025-00392-9
- High evidence
- Clinical
TIR was 34.7% for milk, 38.7% for yoghurt, 45.9% for kefir, and 75.5% for control during the 6-hour post snack period, with TIR on the control day significantly higher than the three snack days (p < 0.001).
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- 10 grams of carbohydrate