peanut butter and Achieved Sustained Unresponsiveness

• Peanut Oral Immunotherapy in Children with High-Threshold Peanut Allergy.

  • 2025-02-25
  • RCT · n = 73
  • NEJM evidence 4(3)
  • • Scott H Sicherer
    • Supinda Bunyavanich
    • M Cecilia Berin
    • Tracy Lo
    • Marion Groetch
    • Allison Schaible
    • Susan A Perry
    • Lisa M Wheatley
    • Patricia C Fulkerson
    • Helena L Chang
    • Mayte Suárez-Fariñas
    • Hugh A Sampson
    • Julie Wang

  • PubMed: 39928078
  • DOI: 10.1056/evidoa2400306

  2 Insights on

  • Achieved Sustained Unresponsiveness

  • High evidence
  • Children

  sustained unresponsiveness occurred in 68.4% (26/38) on P-OIT versus 8.6% (3/35) tolerating 9043 mg among those avoiding (between-group difference, 59.9 percentage points; 95% CI, 42.4 to 77.3).

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes