Peanut Oral Immunotherapy in Children with High-Threshold Peanut Allergy.
- 2025-02-25
- RCT · n = 73
- NEJM evidence 4(3)
- Scott H Sicherer
- Supinda Bunyavanich
- M Cecilia Berin
- Tracy Lo
- Marion Groetch
- Allison Schaible
- Susan A Perry
- Lisa M Wheatley
- Patricia C Fulkerson
- Helena L Chang
- Mayte Suárez-Fariñas
- Hugh A Sampson
- Julie Wang
- PubMed: 39928078
- DOI: 10.1056/evidoa2400306
- High evidence
- Children
The primary analysis with prespecified multiple imputation for missing values showed 100% success for ingestion versus 21.0% for avoidance (between-group difference, 79.0 percentage points; 95% CI, 64.6 to 93.5; P<0.001).
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes