pomegranate and Increased High-Density Lipoprotein Cholesterol

• An updated systematic review and meta-analysis of pomegranate consumption on lipid profile.

  • 2025-06
  • Meta-Analysis · n = 2,695
  • Prostaglandins & other lipid mediators 178
  • • Wengong Cheng
    • Kaiqin Liang
    • Aiqiong Huang

  • PubMed: 40216355
  • DOI: 10.1016/j.prostaglandins.2025.106992

  4 Insights on

  • Increased High-Density Lipoprotein Cholesterol

  • High evidence

  Results indicated that pomegranate intake significantly increased HDL-C levels (mean difference: 2.50 mg/dL, 95 % CI: 1.00-4.00, p < 0.05)

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

• Impacts of supplementation with pomegranate on cardiometabolic risk factors: A systematic review and dose-response meta-analysis.

  • 2025-10
  • Meta-Analysis · n = 2,306
  • Nutrition, metabolism, and cardiovascular diseases : NMCD 35(10)
  • • Shooka Mohammadi
    • Javad Heshmati
    • Nima Baziar
    • Somayeh Ziaei
    • Farnaz Farsi
    • Sara Ebrahimi
    • Tofigh Mobaderi
    • Tanin Mohammadi
    • Hassan Mir

  • PubMed: 40617711
  • DOI: 10.1016/j.numecd.2025.104154

  16 Insights on

  • Increased High-Density Lipoprotein Cholesterol

  • High evidence

  PO supplementation substantially ... elevating high-density lipoprotein (HDL) levels (SMD: 0.27 mg/dL, 95 % CI: 0.08, 0.47; P < 0.001)

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes