Propolis as a Natural Remedy in Reducing Dental Plaque and Gingival Inflammation: A Systematic Review and Meta-Analysis.
- 2025-09-08
- Review
- Journal of functional biomaterials 16(9)
- Magdalena Sycińska-Dziarnowska
- Liliana Szyszka-Sommerfeld
- Monika Bugajska
- Magdalena Ziąbka
- Izabela Szućko-Kociuba
- Gianrico Spagnuolo
- Krzysztof Woźniak
- Hyo-Sang Park
- PubMed: 41003407
- DOI: 10.3390/jfb16090336
- Low evidence
For PI, the pooled standardized mean difference (SMD) was 1.74 (95% CI: 0.19-3.29; p = 0.036), with low between-study heterogeneity (I2 = 13.7%). Propolis mouthwashes demonstrated large effect sizes, significantly reducing plaque accumulation.
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes