Prune Consumption Attenuates Proinflammatory Cytokine Secretion and Alters Monocyte Activation in Postmenopausal Women: Secondary Outcome Analysis of a 12-Mo Randomized Controlled Trial: The Prune Study.
- 2024-05
- RCT · n = 235
- The Journal of nutrition 154(5)
- Janhavi J Damani
- Ester S Oh
- Mary Jane De Souza
- Nicole Ca Strock
- Nancy I Williams
- Cindy H Nakatsu
- Hang Lee
- Connie Weaver
- Connie J Rogers
- PubMed: 37984741
- DOI: 10.1016/j.tjnut.2023.11.014
- High evidence
- Large Human Trial
- Elderly
the percent change from baseline in IL-1β, IL-6, and IL-8 secretion was lower in the 100 g prune/d group compared with the control group (-8.9% ± 61.6%, -4.3% ± 75.3%, -14.3% ± 60.8% in 100 g prune/d compared with 46.9% ± 107.4%, 16.9% ± 70.6%, 39.8% ± 90.8% in control for IL-1β, IL-6, and IL-8, respectively; all P < 0.05)
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes
- Dose
- 100 g prune/d