prune and Reduced Monocyte Adhesion

Doses used in studies

g/day: 50–100 (median 75, IQR 50–100) — 1 study

Time to effect

Median: 12.2 months · IQR 12.2 months–12.2 months · Range 12.2 months–12.2 months — Reported in 1 of 1 study

1 of 1 paper

Prune Consumption Attenuates Proinflammatory Cytokine Secretion and Alters Monocyte Activation in Postmenopausal Women: Secondary Outcome Analysis of a 12-Mo Randomized Controlled Trial: The Prune Study.

2024-05
RCT · n = 235
The Journal of nutrition 154(5)
- Janhavi J Damani
- Ester S Oh
- Mary Jane De Souza
- Nicole Ca Strock
- Nancy I Williams
- Cindy H Nakatsu
- Hang Lee
- Connie Weaver
- Connie J Rogers

PubMed: 37984741
DOI: 10.1016/j.tjnut.2023.11.014

10 Insights on

Reduced Monocyte Adhesion

High evidence
Large Human Trial
Elderly

percent change from baseline in circulating activated monocytes was lower in the 100 g prune/d group compared with the control group (mean ± SD, -1.8% ± 4.0% in 100 g prune/d compared with 0.1% ± 2.9% in control; P < 0.01)

Effect: Beneficial
Effect size: Small
Significant: Yes
Dose: 100 g prune/d