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Evidence-Based Supplement Research

Evidence-Based Supplement Research

prune and Reduced Monocyte Chemoattractant Protein-1 Level

Doses used in studies

g/day: 50–100 (median 75, IQR 50–100) — 1 study

Time to effect

Median: 12.2 months · IQR 12.2 months–12.2 months · Range 12.2 months–12.2 months — Reported in 1 of 1 study

1 of 1 paper

Prune Consumption Attenuates Proinflammatory Cytokine Secretion and Alters Monocyte Activation in Postmenopausal Women: Secondary Outcome Analysis of a 12-Mo Randomized Controlled Trial: The Prune Study.
- 2024-05
- RCT · n = 235
- The Journal of nutrition 154(5)
- - Janhavi J Damani
  - Ester S Oh
  - Mary Jane De Souza
  - Nicole Ca Strock
  - Nancy I Williams
  - Cindy H Nakatsu
  - Hang Lee
  - Connie Weaver
  - Connie J Rogers
- PubMed: 37984741
- DOI: 10.1016/j.tjnut.2023.11.014
10 Insights on
- Reduced Monocyte Chemoattractant Protein-1 Level
- High evidence
- Large Human Trial
- Elderly
Prune supplementation did not alter hs-CRP, TAC, 8-isoprostane, and plasma cytokine concentrations.
Effect
Neutral
Effect size
Small
Significant
No
Dose
50 g prune/d and 100 g prune/d