Across 3 review studies, all 3 report beneficial effects of psyllium on reducing blood cholesterol, with 2 finding statistically significant reductions. The predominant effect size is moderate, with one meta-analysis reporting a weighted mean difference of -9.05 mg/dL for total cholesterol. Doses and study durations were not consistently reported across studies.
Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). All three studies are reviews, not individual trials, and two provide limited quantitative detail.
Psyllium showed a significant decrease in ... total Cholesterol; cholesterol: (Weighted Mean Differences: -9.05; 95% Confidence Intervals: -13.71, -4.40; p-value < 0.05)
Psyllium may help to regulate blood glucose, blood pressure and cholesterol levels.
the addition of a soluble fiber product, most notably psyllium, improves blood lipid profiles, particularly total and low-density lipoprotein cholesterol