Pygeum Bark and Improved Urinary Flow

Safety in these studies

dropoutNo significant difference13% (P. africanum), 11% (placebo), 8% (other controls); P = 0.4 versus placebo
The overall dropout rate was 12% and was similar for P. africanum (13%), placebo (11%), and other controls (8%; P = 0.4 versus placebo and P = 0.5 versus other controls).
from: Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a system
Overall tolerabilityReported
Adverse effects due to P. africanum were mild and similar to placebo.
from: Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a system

1 of 1 paper

Pygeum africanum for the treatment of patients with benign prostatic hyperplasia: a systematic review and quantitative meta-analysis.

2000-12
Systematic Review · n = 562
The American journal of medicine 109(8)
- A Ishani
- R MacDonald
- D Nelson
- I Rutks
- T J Wilt

PubMed: 11099686
DOI: 10.1016/s0002-9343(00)00604-5

5 Insights on

Improved Urinary Flow

High evidence
Clinical

Compared with placebo in 6 studies, P. africanum provided a moderately large improvement in the combined outcome of urologic symptoms and flow measures as assessed by an effect size defined by the difference of the mean change for each outcome divided by the pooled standard deviation for each outcome (-0.8 SD [95% confidence interval (CI): -1.4 to -0.3]).

Effect: Beneficial
Effect size: Moderate
Significant: Yes