Red clover for treatment of hot flashes and menopausal symptoms: A systematic review and meta-analysis.
- 2015-10-15
- Meta-Analysis
- Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 36(3)
- M Ghazanfarpour
- R Sadeghi
- R Latifnejad Roudsari
- I Khorsand
- T Khadivzadeh
- B Muoio
- PubMed: 26471215
- DOI: 10.3109/01443615.2015.1049249
- High evidence
- Clinical
The mean frequency of hot flashes in red clover groups was lower compared with that in the control groups (close to statistical significance). Difference in means (MD) of hot flashes frequency was - 1.99 (- 4.12-0.139; p = 0.067; heterogeneity P > 0.01; I(2) = 94.93%; Random effect model).
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- not explicitly stated for the meta-analysis overall; 80 mg dose used for vaginal atrophy outcomes