saccharomyces boulardii and Reduced Stool Frequency

• Role of a probiotic (Saccharomyces boulardii) in management and prevention of diarrhoea.

  • 2006-10-31
  • RCT · n = 100
  • World Journal of Gastroenterology 12(28)
  • • AG Billoo
    • Ma Memon
    • S. Khaskheli
    • G. Murtaza
    • K. Iqbal
    • M. Shekhani
    • Ahson Siddiqi

  • PubMed: 16874872
  • DOI: 10.3748/WJG.V12.I28.4557

  5 Insights on

  • Reduced Stool Frequency

  • High evidence
  • Highly Cited

  By d 3 it reduced to 2.7 and 4.2 stools per d respectively and by d 6 it reduced to 1.6 (S. boulardii Group) and 3.3 (control group).

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

  Dose

  250 mg bid

• Efficacy and Safety of Saccharomyces boulardii for Acute Diarrhea

  • 2014-07-01
  • Systematic Review
  • Pediatrics 134(1)
  • • S. Feizizadeh
    • A. Salehi-abargouei
    • Vajihe Akbari

  • PubMed: 24958586
  • DOI: 10.1542/peds.2013-3950

  4 Insights on

  • Reduced Stool Frequency

  • High evidence
  • Highly Cited

  Pooling data from trials showed that S. boulardii significantly reduced ... stool frequency on day 2 (MD, -0.74; 95% CI, -1.38 to -0.10).

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

• Saccharomyces boulardii in acute childhood diarrhoea: a randomized, placebo‐controlled study

  • 2007-03-22
  • RCT
  • Acta Paediatrica 96(4)
  • • Gladys Villarruel
    • Daniel Rubio
    • F. Lopez
    • Julio Cintioni
    • Rubén Gurevech
    • G. Romero
    • Y. Vandenplas

  • PubMed: 17306006
  • DOI: 10.1111/j.1651-2227.2007.00191.x

  4 Insights on

  • Reduced Stool Frequency

  • High evidence
  • Highly Cited

  On the 4th day, the patients in the S. boulardii group passed 2.5+/-1.4 stools/day versus 3.5+/-1.8 in the placebo group (p<0.001).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes