Saffron and Reduced Systolic Blood Pressure

• Effects of Saffron Supplementation on Glycolipid Metabolism and Blood Pressure in Patients With Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

  • 2025-02-11
  • Meta-Analysis · n = 1,486
  • Phytotherapy research : PTR 39(5)
  • • Xiaolei Zhang
    • Jinxin Miao
    • Yagang Song
    • Mingsan Miao

  • PubMed: 39931766
  • DOI: 10.1002/ptr.8421

  11 Insights on

  • Reduced Systolic Blood Pressure

  • High evidence
  • Clinical

  saffron supplementation triggered significant reductions in ... systolic blood pressure (SBP) (WMD: -1.15 mmHg; 95% CI: -1.66, -0.64; p < 0.001; I² = 41.8%)

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

• The effect of saffron supplementation on liver and kidney function, blood glucose and pressure in patients with diabetes and prediabetes: A grade assessed systematic review and meta-analysis of randomized controlled trials.

  • 2025-03
  • Meta-Analysis
  • Prostaglandins & other lipid mediators 177
  • • Jia-Wei Zhang
    • Qing Zhao
    • Zhe Li
    • Qian Liu
    • Sha-Sha Zang
    • Sha Liu

  • PubMed: 39818282
  • DOI: 10.1016/j.prostaglandins.2025.106949

  7 Insights on

  • Reduced Systolic Blood Pressure

  • High evidence
  • Clinical

  Saffron supplementation significantly reduced SBP (SMD = -0.57, 95 % CI: -0.8 to -0.34, p = 0.036)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes