Saffron and Reduced Tumor Necrosis Factor Alpha

• The efficacy of saffron supplementation on inflammation and oxidative stress in patients with type-2 diabetes mellitus: a meta-analysis.

  • 2025-08-06
  • Meta-Analysis · n = 261
  • Frontiers in endocrinology 16
  • • Lulu Qin
    • Nini Hu
    • Kejing Wang
    • Lin Chen

  • PubMed: 40842498
  • DOI: 10.3389/fendo.2025.1634982

  6 Insights on

  • Reduced Tumor Necrosis Factor Alpha

  • High evidence
  • Clinical

  The meta-analysis results demonstrated a significant reduction in TNF-α levels following saffron supplementation compared to the placebo group.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes