Soy and Increased Circulating Estradiol Level

• Soy, red clover, and isoflavones and breast cancer: a systematic review.

  • 2013-11-28
  • Systematic Review · n = 131
  • PloS one 8(11)
  • • Heidi Fritz
    • Dugald Seely
    • Gillian Flower
    • Becky Skidmore
    • Rochelle Fernandes
    • Sarah Vadeboncoeur
    • Deborah Kennedy
    • Kieran Cooley
    • Raimond Wong
    • Stephen Sagar
    • Elham Sabri
    • Dean Fergusson

  • PubMed: 24312387
  • DOI: 10.1371/journal.pone.0081968

  5 Insights on

  • Increased Circulating Estradiol Level

  • High evidence
  • Clinical

  Human trials show that soy does not increase circulating estradiol or affect estrogen-responsive target tissues.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  not stated