Soy and Reduced Breast Cancer Mortality

• Soy, red clover, and isoflavones and breast cancer: a systematic review.

  • 2013-11-28
  • Systematic Review · n = 131
  • PloS one 8(11)
  • • Heidi Fritz
    • Dugald Seely
    • Gillian Flower
    • Becky Skidmore
    • Rochelle Fernandes
    • Sarah Vadeboncoeur
    • Deborah Kennedy
    • Kieran Cooley
    • Raimond Wong
    • Stephen Sagar
    • Elham Sabri
    • Dean Fergusson

  • PubMed: 24312387
  • DOI: 10.1371/journal.pone.0081968

  5 Insights on

  • Reduced Breast Cancer Mortality

  • High evidence
  • Clinical

  Soy consumption may be associated with reduced risk of breast cancer incidence, recurrence, and mortality.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

  Dose

  25-50 mg isoflavones (2-3 servings daily)

• A Review of the Clinical and Epidemiologic Evidence Relevant to the Impact of Postdiagnosis Isoflavone Intake on Breast Cancer Outcomes.

  • 2025-03-25
  • Review
  • Current nutrition reports 14(1)
  • • Mark Messina
    • Sarah Nechuta

  • PubMed: 40131602
  • DOI: 10.1007/s13668-025-00640-5

  4 Insights on

  • Reduced Breast Cancer Mortality

  • Low evidence
  • Clinical

  the results from epidemiologic studies indicate postdiagnosis isoflavone intake from soy foods reduces recurrence and possibly mortality from breast cancer

  Effect

  Beneficial

  Effect size

  Small

  Significant

  No

  Dose

  approximately 50 mg isoflavones (two servings of traditional Asian soy foods daily)