Soy and Reduced C-Reactive Protein Levels

• Can soy isoflavones in combination with soy protein change serum levels of C-reactive protein among patients with chronic inflammatory diseases? A systematic review and meta-analysis on randomized controlled trials.

  • 2025-05-12
  • Meta-Analysis
  • Journal of health, population, and nutrition 44(1)
  • • Ali Gholami
    • Bahareh Amirkalali
    • Mitra Hariri

  • PubMed: 40355968
  • DOI: 10.1186/s41043-025-00902-6

  1 Insight on

  • Reduced C-Reactive Protein Levels

  • High evidence
  • Clinical

  The overall estimates revealed that soy isoflavones containing soy protein significantly decreased serum levels of CRP in comparison with control group (weighted mean difference (WMD)= -0.49 mg/L; 95% confidence interval (CI): -0.74, -0.25; P=0<0.001).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes