Soy and Reduced Risk of Major Neurocognitive Disorder

• Association of high consumption of soy products with the risk of cognitive impairment and major neurocognitive disorders: a systematic review and dose-response meta-analysis.

  • 2025-08-21
  • Systematic Review · n = 691
  • Frontiers in nutrition 12
  • • Jialin Yu
    • Hongmei Zeng

  • PubMed: 40917087
  • DOI: 10.3389/fnut.2025.1635844

  1 Insight on

  • Reduced Risk of Major Neurocognitive Disorder

  • High evidence

  The dose-response meta-analysis indicated that a 1-g per day increase in the consumption of soy and natto demonstrated a correlation with an 8 and 14% decrease in the likelihood of developing major neurocognitive disorder, respectively.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  1 g per day increase