Effects of yacon flour associated with an energy restricted diet on intestinal permeability, fecal short chain fatty acids, oxidative stress and inflammation markers levels in adults with obesity or overweight: a randomized, double blind, placebo controlled clinical trial.
- 2021-05-01
- RCT · n = 13
- Archives of endocrinology and metabolism 64(5)
- Adriane Moreira Machado
- Nayara Benedito Martins da Silva
- Renata Maria Pereira de Freitas
- Mariella Bontempo Duca de Freitas
- José Bemício Paes Chaves
- Leandro Licursi Oliveira
- Hércia Stampini Duarte Martino
- Rita de Cássia Gonçalves Alfenas
- PubMed: 34033301
- DOI: 10.20945/2359-3997000000225
- High evidence
- Clinical
A reduction in SCFAs was observed in both groups (Δacetic: -3.16 (-5.07; -0.95) vs. -1.05 (-2.65; 1.11); Δpropionic: -1.05 (-2.60;-0.38) vs. -0.41 (-2.08; 0.09); Δbutyric -0.75 (-1.38; -0.04) vs. -0.28 (-0.98; 0.11), for YAC and CON, respectively). Other variables did not change.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- 25 g/day