facial paraesthesiaIncreased risksix of 147 participants in the ALC > 1500 mg/day group (4.1%) and two of 147 participants in the placebo group (1.4%) discontinued treatment because of adverse events (headache, facial paraesthesia, and gastrointestinal disorders) (P = 0.17)
One placebo-controlled study reported that six of 147 participants in the ALC > 1500 mg/day group (4.1%) and two of 147 participants in the placebo group (1.4%) discontinued treatment because of adverse events (headache, facial paraesthesia, and gastrointestinal disorders) (P = 0.17).
from: Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy.gastrointestinal disordersIncreased risksix of 147 participants in the ALC > 1500 mg/day group (4.1%) and two of 147 participants in the placebo group (1.4%) discontinued treatment because of adverse events (headache, facial paraesthesia, and gastrointestinal disorders) (P = 0.17)
One placebo-controlled study reported that six of 147 participants in the ALC > 1500 mg/day group (4.1%) and two of 147 participants in the placebo group (1.4%) discontinued treatment because of adverse events (headache, facial paraesthesia, and gastrointestinal disorders) (P = 0.17).
from: Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy.headacheIncreased risksix of 147 participants in the ALC > 1500 mg/day group (4.1%) and two of 147 participants in the placebo group (1.4%) discontinued treatment because of adverse events (headache, facial paraesthesia, and gastrointestinal disorders) (P = 0.17)
One placebo-controlled study reported that six of 147 participants in the ALC > 1500 mg/day group (4.1%) and two of 147 participants in the placebo group (1.4%) discontinued treatment because of adverse events (headache, facial paraesthesia, and gastrointestinal disorders) (P = 0.17).
from: Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy.Overall tolerabilityReported
No major side effects were noticed.
from: Clinical usefulness of nutraceutics with acetyl-L-carnitine, α-lipoic acid, phosphatidylseOverall tolerabilityReported
The other two placebo-controlled studies reported no dropouts due to adverse events, and more pain, paraesthesia, and hyperaesthesias in the placebo group than the 3000 mg/day ALC group, but provided no numerical data.
from: Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy.facial paraesthesiaReported
One placebo-controlled study reported that six of 147 participants in the ALC > 1500 mg/day group (4.1%) and two of 147 participants in the placebo group (1.4%) discontinued treatment because of adverse events (headache, facial paraesthesia, and gastrointestinal disorders) (P = 0.17).
from: Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy.gastrointestinal disordersReported
One placebo-controlled study reported that six of 147 participants in the ALC > 1500 mg/day group (4.1%) and two of 147 participants in the placebo group (1.4%) discontinued treatment because of adverse events (headache, facial paraesthesia, and gastrointestinal disorders) (P = 0.17).
from: Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy.gastrointestinal symptomsReported
Nine participants discontinued treatment due to adverse events (ALC: 4 participants, methylcobalamin: 5 participants), which were most commonly gastrointestinal symptoms.
from: Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy.headacheReported
One placebo-controlled study reported that six of 147 participants in the ALC > 1500 mg/day group (4.1%) and two of 147 participants in the placebo group (1.4%) discontinued treatment because of adverse events (headache, facial paraesthesia, and gastrointestinal disorders) (P = 0.17).
from: Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy.hyperaesthesiasReported
The other two placebo-controlled studies reported no dropouts due to adverse events, and more pain, paraesthesia, and hyperaesthesias in the placebo group than the 3000 mg/day ALC group, but provided no numerical data.
from: Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy.painReported
The other two placebo-controlled studies reported no dropouts due to adverse events, and more pain, paraesthesia, and hyperaesthesias in the placebo group than the 3000 mg/day ALC group, but provided no numerical data.
from: Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy.paraesthesiaReported
The other two placebo-controlled studies reported no dropouts due to adverse events, and more pain, paraesthesia, and hyperaesthesias in the placebo group than the 3000 mg/day ALC group, but provided no numerical data.
from: Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy.