Casein Hydrolysate Containing Milk-Derived Peptides Reduces Facial Pigmentation Partly by Decreasing Advanced Glycation End Products in the Skin: A Randomized Double-Blind Placebo-Controlled Trial.
- 2021-04
- RCT
- Rejuvenation research 24(2)
- Michiya Igase
- Yoko Okada
- Keiji Igase
- Sayaka Matsumoto
- Kensuke Senzaki
- Masayuki Ochi
- Yasumasa Ohyagi
- Sho-Ichi Yamagishi
- PubMed: 32829654
- DOI: 10.1089/rej.2020.2343
- High evidence
- Clinical
Treatment with casein hydrolysate, but not placebo significantly reduced triglycerides and facial pigmentation area.
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes