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Evidence-Based Supplement Research

Evidence-Based Supplement Research

L-Arginine and Improved Activities of Daily Living

Doses used in studies

g/day: 1.66 (median 1.66, IQR 1.66–1.66) — 1 study

Time to effect

Median: 4 weeks · IQR 4 weeks–4 weeks · Range 4 weeks–4 weeks — Reported in 1 of 1 study

1 of 1 paper

Impact of L-arginine and liposomal vitamin C supplementation on quality of life and daily life activities in patients with COPD: a randomized, multicenter, single blind, placebo-controlled trial (ILDA study).
- 2025-06
- RCT · n = 150
- European journal of internal medicine 136
- - Dejan Radovanovic
  - Juan Camilo Signorello
  - Giuseppe Fuccia
  - Giada Lazzaroni
  - Fiammetta Danzo
  - Gualtiero Maria Guandalini
  - Federica Massaro
  - Francesco Tursi
  - Pierachille Santus
- PubMed: 40316462
- DOI: 10.1016/j.ejim.2025.04.039
3 Insights on
- Improved Activities of Daily Living
- High evidence
- Large Human Trial
- Clinical
LCADL total score (-1.0 (-3.0;0.0); P = 0.005); LCADL housework (-1.0 (-3.0;0.0); P < 0.001) and LCADL free time (0.0 (-1.0;0.0); P = 0.003).
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
1.66 g twice daily