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Evidence-Based Supplement Research

Evidence-Based Supplement Research

L-Carnitine and Reduced LDL Cholesterol

Doses used in studies

L-Carnitine · mg/day: 3,000 (median 3,000, IQR 3,000–3,000) — 1 study

Time to effect

Median: 6 weeks · IQR 6 weeks–6 weeks · Range 6 weeks–6 weeks — Reported in 1 of 2 studies

2 of 2 papersPopulation:

Adding L-carnitine to antagonist ovarian stimulation doesn't improve the outcomes of IVF/ ICSI cycle in patients with polycystic ovarian syndrome: a double-blind randomized clinical trial.
- 2024-01-09
- RCT · n = 110
- Journal of ovarian research 17(1)
- - Maryam Hafezi
  - Arezoo Arabipoor
  - Firouzeh Ghaffari
  - Samira Vesali
  - Maryam Zareei
  - Zahra Hajinaghibali Hessari
- PubMed: 38191449
- DOI: 10.1186/s13048-023-01319-7
13 Insights on
- Reduced LDL Cholesterol
- High evidence
- Large Human Trial
- Clinical
LDL (P < 0.001) … have significantly decreased in women after consuming L-carnitine supplementation
Effect
Beneficial
Effect size
Large
Significant
Yes
Dose
3000 mg/day (3 tablets daily of 1000 mg L-carnitine)
The effects of L-carnitine supplementation on cardiovascular risk factors in participants with impaired glucose tolerance and diabetes: a systematic review and dose-response meta-analysis.
- 2024-07-31
- Review · n = 2,900
- Diabetology & metabolic syndrome 16(1)
- - Rezvan Gheysari
  - Mahlagha Nikbaf-Shandiz
  - Amir Mehdi Hosseini
  - Niloufar Rasaei
  - Shabnam Hosseini
  - Hossein Bahari
  - Omid Asbaghi
  - Samira Rastgoo
  - Kian Goudarzi
  - Farideh Shiraseb
  - Reza Behmadi
- PubMed: 39085907
- DOI: 10.1186/s13098-024-01415-8
11 Insights on
- Reduced LDL Cholesterol
- High evidence
L-carnitine supplementation had a significant effect on LDL (WMD = - 12.66 mg/dl, p < 0.001)
Effect
Beneficial
Effect size
Moderate
Significant
Yes