L-Citrulline and Reduced Triglyceride Levels

Doses used in studies

g/day: 3 (median 3, IQR 3–3) — 1 study

Time to effect

Median: 10 weeks · IQR 9 weeks–11 weeks · Range 8 weeks–2.8 months — Reported in 2 of 2 studies

2 of 2 papers

Impact of L-Citrulline Supplementation and HIIT on Lipid Profile, Arterial Stiffness, and Fat Mass in Obese Adolescents with Metabolic-Dysfunction-Associated Fatty Liver Disease: A Randomized Clinical Trial.
- 2025-01-23
- RCT · n = 15
- Nutrients 17(3)
- - Alan Arturo Rodríguez-Carrillo
  - Mario Ramón Espinoza-Vargas
  - Katya Vargas-Ortiz
  - Lorena Del Rocío Ibarra-Reynoso
  - Monserrat Olvera-Juárez
  - Armando Gómez-Ojeda
  - Ma Eugenia Garay-Sevilla
  - Arturo Figueroa
- PubMed: 39940261
- DOI: 10.3390/nu17030402
9 Insights on
- Reduced Triglyceride Levels
- High evidence
- Rigorous Journal
- Clinical
Compared to L-cit, HIIT + L-cit improved ... triglycerides (p = 0.02)
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
not specified
The impact of L-citrulline supplementation on glucose homeostasis, lipid profile, and some inflammatory factors in overweight and obese patients with type 2 diabetes: A double-blind randomized placebo-controlled trial.
- 2021-04-20
- RCT · n = 54
- Phytotherapy research : PTR 35(6)
- - Samaneh Azizi
  - Reza Mahdavi
  - Majid Mobasseri
  - Soghra Aliasgharzadeh
  - Fatemeh Abbaszadeh
  - Mehrangiz Ebrahimi-Mameghani
- PubMed: 33876875
- DOI: 10.1002/ptr.6997
10 Insights on
- Reduced Triglyceride Levels
- High evidence
- Clinical
Despite the significant decrease in serum levels of triglyceride (p = .027) ... no significant differences were found for these parameters between the groups.
Effect
Neutral
Effect size
Small
Significant
No
Dose
3 g/day

L-Citrulline and Reduced Triglyceride Levels

Impact of L-Citrulline Supplementation and HIIT on Lipid Profile, Arterial Stiffness, and Fat Mass in Obese Adolescents with Metabolic-Dysfunction-Associated Fatty Liver Disease: A Randomized Clinical Trial.

The impact of L-citrulline supplementation on glucose homeostasis, lipid profile, and some inflammatory factors in overweight and obese patients with type 2 diabetes: A double-blind randomized placebo-controlled trial.