N-Acetyl Cysteine and Improved Bowel Movement Frequency

• Evaluating the efficacy of N-acetylcysteine in diminishing the duration and frequency of rotavirus-induced gastroenteritis: a preliminary randomized, placebo-controlled, double-blind clinical trial.

  • 2025-03-12
  • RCT · n = 71
  • BMC pediatrics 25(1)
  • • Behrooz Heydari
    • Majid Aflatonian
    • Mina Bagherizadeh
    • Farahnaz Hoseinzade
    • Fatemeh Saghafi

  • PubMed: 40069676
  • DOI: 10.1186/s12887-025-05534-7

  2 Insights on

  • Improved Bowel Movement Frequency

  • High evidence
  • Clinical

  During the diarrhea period, the number of bowel movements in the NAC group was recorded at 28.1 ± 21.6 times, whereas in the placebo group, it was 35.3 ± 33.1 times, yielding a p-value of 0.409.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  60 mg/kg/day