N-Acetyl Cysteine and Reduced Length of Hospital Stay

• N-acetyl cysteine versus standard of care for non-acetaminophen induced acute liver injury: a systematic review and meta-analysis.

  • 2021-09
  • Meta-Analysis · n = 11
  • Annals of hepatology 24
  • • Dhan Bahadur Shrestha
    • Pravash Budhathoki
    • Yub Raj Sedhai
    • Anurag Adhikari
    • Ayusha Poudel
    • Barun Aryal
    • Ramkaji Baniya

  • PubMed: 33722689
  • DOI: 10.1016/j.aohep.2021.100340

  3 Insights on

  • Reduced Length of Hospital Stay

  • High evidence
  • Clinical

  reduced mean duration of hospital stay by 6.52 days (95% CI, -12.91 to -0.13)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Evaluation of nebulized N-acetyl cysteine in outcome of esophageal atresia with tracheoesophegeal fistula.

  • 2020-12
  • Clinical Trial · n = 30
  • Journal of pediatric surgery 55(12)
  • • Gurmeet Singh
    • Anand Pandey
    • Gaurav Shandilya
    • Archika Gupta
    • J D Rawat
    • Ashish Wakhlu
    • S N Kureel

  • PubMed: 32467034
  • DOI: 10.1016/j.jpedsurg.2020.04.013

  3 Insights on

  • Reduced Length of Hospital Stay

  • High evidence
  • Clinical

  Patients' discharge was significantly (p = 0.01) earlier in cases.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  2 mL of 10% NAC, nebulized (2:5 dilution, every six hourly)