Taurine and Reduced Fatigue

• A randomized controlled trial of L-taurine for fatigue in decompensated cirrhosis.

  • 2026-04-24
  • RCT · n = 161
  • Hepatology communications 10(5)
  • • Swarup Sasidharan
    • Cyriac Abby Philips
    • Ajit Tharakan
    • Rizwan Ahamed
    • Tharun Tom Oommen
    • John Menachery
    • Rosh Varghese
    • Philip Augustine

  • PubMed: 42043864
  • DOI: 10.1097/hc9.0000000000000938

  3 Insights on

  • Reduced Fatigue

  • High evidence
  • Large Human Trial

  The mean FAS change was -6.83±8.70 (standard care) versus -8.08±7.95 (taurine), with no significant difference (mean difference -1.25; 95% CI: -3.55 to 1.05; p=0.288; Cohen's d=-0.15).

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  1000 mg/d