Best Supplements for Reduced Fatigue
Ranked by research evidence. Compare 30 supplements across 35 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Low evidence4 studies
Across 4 studies, all reported beneficial effects of Lactobacillus brevis SBC8803 on reducing fatigue, with one randomized controlled trial (RCT) showing a statistically significant moderate effect. The remaining three studies were reviews that reported small beneficial effects. Available evidence comes primarily from reviews and one small RCT; the most-studied population appears to be healthy adults, though specifics are limited.
- Very low evidence3 studies
Across 3 studies, all reported beneficial effects of Lactobacillus salivarius UCC118 on reducing fatigue, with effect sizes ranging from small to moderate. One study (animal model) found statistically significant reductions in fatigue biomarkers (lactate, BUN, ammonia, creatine kinase). The evidence is drawn from one animal trial and two narrative reviews, with no consistent dose, form, or population data reported across studies.
- LowLactobacillus brevis SBC8803Across 4 studies, all reported beneficial effects of Lactobacillus brevis SBC8803 on reducing fatigue, with one randomized controlled trial (RCT) showing a statistically significant moderate effect. The remaining three studies were reviews that reported small beneficial effects. Available evidence comes primarily from reviews and one small RCT; the most-studied population appears to be healthy adults, though specifics are limited.4 beneficial4 studies
- Very lowLactobacillus salivarius UCC118Across 3 studies, all reported beneficial effects of Lactobacillus salivarius UCC118 on reducing fatigue, with effect sizes ranging from small to moderate. One study (animal model) found statistically significant reductions in fatigue biomarkers (lactate, BUN, ammonia, creatine kinase). The evidence is drawn from one animal trial and two narrative reviews, with no consistent dose, form, or population data reported across studies.3 beneficial3 studies