Skip to main content
Evidence-Based Supplement Research
Evidence-Based Supplement Research
Pillser
Search
Sign UpLog In
New evidence

A probiotic blend improved constipation at 4 weeks in a trial — but the effect faded by week 8, suggesting ongoing intake may be needed.

This is among the first controlled studies to test Bifidobacterium lactis UABla-12 for constipation, but because the probiotic was a multi-strain formula, the specific contribution of that single strain remains unclear — treat this as early, not conclusive, evidence.

In a randomized trial, people taking the probiotic blend Lacto-5X reported less straining, firmer stools, and less abdominal pain after four weeks compared to placebo. However, those benefits were not maintained at eight weeks, meaning any relief likely requires continued daily use. The formula contained multiple bacterial strains, so it's impossible to know how much of the effect came from the specific Bifidobacterium lactis UABla-12 strain highlighted here.

Where this fits in the evidence

This is among the first studies we've indexed on Bifidobacterium lactis UABla-12 for Improved Constipation — treat it as an early signal until more research accumulates.

The study

Impact of Probiotic Formula (Lacto-5X) on Constipation: Improvements in Gastrointestinal Symptoms, Gut Microbiome, and Metabolites.

  • Randomized Controlled Trial (RCT)
  • 2025-04-09
  • Journal of microbiology and biotechnology
More on Bifidobacterium lactis UABla-12More on Improved Constipation

This is a plain-language summary of a research finding, not medical advice. Pillser surfaces research signals to help you decide what's worth investigating — always consult a qualified professional before changing what you take.

Back to top