Big effect
Propolis mouthwash slashed cavity-causing bacteria by more than a factor of 10 in people with braces — but the effect may not translate to everyone.
This is one of the first rigorous trials to test propolis against cavity bacteria, and the result is unusually large — but until it's replicated in broader populations, consider it a promising early signal, not a settled fact.
In a 9-month trial on 120 people with orthodontic braces, a propolis mouthwash reduced Streptococcus mutans—the main bacteria behind cavities—from about 4.4 to 0.9 on a logarithmic scale, a dramatic drop that outperformed both fluoride and probiotic rinses. The study also found lower levels of an oxidative stress marker, suggesting added benefit. However, because the participants all had braces (a high-risk group for plaque buildup), it's unclear how well the results apply to people without orthodontic appliances.
Where this fits in the evidence
This is among the first studies we've indexed on Propolis for Reduced Streptococcus Mutans Levels — treat it as an early signal until more research accumulates.
The study
- Randomized Controlled Trial (RCT)
- n = 120
- 2025-12
- International orthodontics
This is a plain-language summary of a research finding, not medical advice. Pillser surfaces research signals to help you decide what's worth investigating — always consult a qualified professional before changing what you take.