New evidence
Saffron supplementation linked to a moderate reduction in systolic blood pressure in people with diabetes and prediabetes — but the study found no effect on diastolic pressure, and the effect size is not clinically important.
This is the first solid evidence for saffron on blood pressure in this clinical group, but because it's a single, early meta-analysis with a modest effect that wasn't mirrored in other key outcomes, the finding should be seen as intriguing but far from proven.
In a meta-analysis of patients with diabetes and prediabetes, saffron supplementation significantly reduced systolic blood pressure (the top number) by a moderate amount, along with fasting blood sugar and a liver enzyme. However, it did not lower diastolic blood pressure, other liver markers, or kidney function tests, and the authors noted the blood pressure drop wasn't large enough to matter in practice.
Where this fits in the evidence
This is among the first studies we've indexed on Saffron for Reduced Systolic Blood Pressure — treat it as an early signal until more research accumulates.
The study
- Meta-Analysis
- 2025-03
- Prostaglandins & other lipid mediators
This is a plain-language summary of a research finding, not medical advice. Pillser surfaces research signals to help you decide what's worth investigating — always consult a qualified professional before changing what you take.