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Evidence-Based Supplement Research
Evidence-Based Supplement Research
Myth-buster

Vitamin D supplementation didn't budge a key fertility marker in a meta-analysis of 992 women — the overall effect was null, though a subgroup hinted at a possible drop in women with already-high baseline AMH.

This is among the first meta-analyses on vitamin D for ovarian reserve, and while it found no overall benefit, the substantial heterogeneity in the studies means the question isn't settled — treat the null result as a strong caution, not the final word.

The meta-analysis pooled 992 reproductive-aged women and found that vitamin D supplements did not significantly change anti-Müllerian hormone (AMH) levels — a blood marker used to estimate remaining egg supply. Subgroup results suggested a possible small reduction in AMH among women with high starting levels, but the overall evidence is moderate and the studies varied a lot, so the finding should be viewed as preliminary.

Where this fits in the evidence

This is among the first studies we've indexed on Vitamin D for Changed Anti-Müllerian Hormone Level — treat it as an early signal until more research accumulates.

This is a plain-language summary of a research finding, not medical advice. Pillser surfaces research signals to help you decide what's worth investigating — always consult a qualified professional before changing what you take.

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