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Evidence-Based Supplement Research
Evidence-Based Supplement Research
Surprising

A local vitamin D3 injection after braces kept teeth from drifting back over 3 months — but the same study found no effect on arch width or perimeter changes.

This is an early, small clinical trial suggesting a novel use for vitamin D in orthodontics, but the benefit was narrow (only one measure of relapse improved) and the approach (injected locally, not taken orally) doesn't translate to a supplement you can buy — so treat it as a curiosity, not a takeaway.

Researchers injected vitamin D3 into the gums of people who had just finished orthodontic treatment and tracked tooth movement for three months. The control group showed significantly more relapse (teeth shifting back) starting at week 8, but other measures of stability — like changes in arch width or perimeter — showed no difference between groups. Because this is among the first studies on this specific use, the results need replication before drawing any practical conclusions.

Where this fits in the evidence

This is among the first studies we've indexed on Vitamin D3 for Reduced Orthodontic Relapse — treat it as an early signal until more research accumulates.

The study

Impact of Vitamin D3 on Postorthodontic Treatment Stability: A Randomized Controlled Trial.

  • Randomized Controlled Trial (RCT)
  • 2025-03-05
  • The journal of contemporary dental practice

This is a plain-language summary of a research finding, not medical advice. Pillser surfaces research signals to help you decide what's worth investigating — always consult a qualified professional before changing what you take.

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