Acute Liver Failure
Acute liver failure is a sudden, severe liver dysfunction characterized by hepatic encephalopathy and impaired protein synthesis in individuals without preexisting liver disease, commonly caused by hepatitis viruses or drugs like acetaminophen. Classified by onset speed—hyperacute (within 1 week), acute (8–28 days), and subacute (4–12 weeks)—this condition signals severe liver damage and its outcomes are highly influenced by both the rapidity of onset and underlying cause.
Health Outcomes
- Absence of Bacterial Translocation to Liver or Spleen
- Alleviated Organ Injury
- Alleviated Symptoms in Acetaminophen-Induced Model
- Altered Liver Biomarker Level
- Altered Plasma Metabolite Levels
- Changed Albumin Level
- Changed Clinical Chemistry Measure
- Elevated Acetic Acid Levels
- Elevated Lactate Levels
- Elevated Serum Enzyme Levels
- Enhanced Active Metabolite Levels
- Enhanced Antioxidant Metabolism
- Improved Acute Liver Injury
- Improved Alcohol-Associated Liver Disease Parameters
- Improved Enzyme Levels (ADH, ALDH)
- Improved Hepatic Damage
- Improved Hepatic Function
- Improved Liver Enzyme Level
- Increased Alkaline Phosphatase Activity in Skin Mucus
- Increased Anion Gap
- Increased Aspartate Aminotransferase Concentration
- Increased Aspartate Transferase Level
- Increased Cellular Apoptosis
- Increased Conjugated Bile Acid Levels
- Increased Enzyme Production
- Increased Hepatic Glutathione Content
- Increased Lactic Acid Levels
- Increased Liver Enzyme Levels
- Increased PT/INR
- Increased Plasma GLDH
- Induced Apoptosis
- Liver Protection from Aflatoxin B1 Damage
- Maintained Safety with Repeated Oral Exposure
- No Illness or Death from Bacterial Translocation (Intraperitoneal Administration)
- No Long-Term Impact on Gut Microbiota
- Normal Safety Parameters
- Normalized INR
- Prolonged INR
- Reduced Abnormal Increase in Bilirubin
- Reduced Ammonia Excretion
- Reduced Ammonia Levels
- Reduced Anticoagulation / Increased Warfarin Variability
- Reduced Aspartate Transaminase Activity
- Reduced Body Temperature
- Reduced Butyrylcholinesterase Activity
- Reduced Child-Pugh Score
- Reduced Cholic Acid Level
- Reduced Coagulation Marker Level
- Reduced Cytotoxicity
- Reduced Ferroptosis
- Reduced Fresh Frozen Plasma Transfusion
- Reduced GPT Level
- Reduced Glutamyl Pyruvic Transaminase Levels
- Reduced Hepatic Damage Indices
- Reduced Hepatic Encephalopathy
- Reduced Isoleucine Level
- Reduced Liver Enzyme Activity
- Reduced Liver Function
- Reduced Liver Function Indicators
- Reduced Liver Injury
- Reduced Liver Injury Marker
- Reduced Liver Transplantation Requirement
- Reduced Need for Continuous Renal Replacement Therapy
- Reduced Organ Failure Severity
- Reduced Organ Injury
- Reduced Plasma Urea Level
- Reduced Prothrombin Time
- Reduced Short-term Mortality
- Reduced Urea Level
- Shortened Oliguria Period
- Stabilized Total Bilirubin Levels