Acute Liver Failure
Acute liver failure is a sudden, severe liver dysfunction characterized by hepatic encephalopathy and impaired protein synthesis in individuals without preexisting liver disease, commonly caused by hepatitis viruses or drugs like acetaminophen. Classified by onset speed—hyperacute (within 1 week), acute (8–28 days), and subacute (4–12 weeks)—this condition signals severe liver damage and its outcomes are highly influenced by both the rapidity of onset and underlying cause.
Health Outcomes
- Absence of Bacterial Translocation to Liver or Spleen
- Alleviated Organ Injury
- Alleviated Symptoms in Acetaminophen-Induced Model
- Altered Plasma Metabolite Levels
- Changed Albumin Level
- Elevated Acetic Acid Levels
- Elevated Lactate Levels
- Elevated Serum Enzyme Levels
- Enhanced Active Metabolite Levels
- Enhanced Antioxidant Metabolism
- Improved Acute Liver Injury
- Improved Alcohol-Associated Liver Disease Parameters
- Improved Enzyme Levels (ADH, ALDH)
- Improved Hepatic Damage
- Improved Hepatic Function
- Increased Alkaline Phosphatase Activity in Skin Mucus
- Increased Anion Gap
- Increased Aspartate Aminotransferase Concentration
- Increased Aspartate Aminotransferase Level
- Increased Aspartate Transferase Level
- Increased Blood Lactate Level
- Increased Cellular Apoptosis
- Increased Conjugated Bile Acid Levels
- Increased Enzyme Production
- Increased Hepatic Glutathione Content
- Increased Lactic Acid Levels
- Increased Liver Enzyme Levels
- Increased PT/INR
- Increased Plasma GLDH
- Induced Apoptosis
- Liver Protection from Aflatoxin B1 Damage
- Maintained Safety with Repeated Oral Exposure
- No Illness or Death from Bacterial Translocation (Intraperitoneal Administration)
- No Long-Term Impact on Gut Microbiota
- Normal Safety Parameters
- Normalized INR
- Prolonged INR
- Reduced Abnormal Increase in Bilirubin
- Reduced Aminotransferase Level
- Reduced Ammonia Excretion
- Reduced Ammonia Levels
- Reduced Anticoagulation / Increased Warfarin Variability
- Reduced Apolipoprotein B Level
- Reduced Aspartate Transaminase Activity
- Reduced Blood Ammonia Level
- Reduced Body Temperature
- Reduced Butyrylcholinesterase Activity
- Reduced Cholic Acid Level
- Reduced Cytotoxicity
- Reduced Ferroptosis
- Reduced Fibrinogen Level
- Reduced Fresh Frozen Plasma Transfusion
- Reduced GPT Level
- Reduced Glutamyl Pyruvic Transaminase Levels
- Reduced Hepatic Damage Indices
- Reduced Hepatic Encephalopathy
- Reduced Hyperbilirubinemia Incidence
- Reduced Isoleucine Level
- Reduced Liver Enzyme Activity
- Reduced Liver Function
- Reduced Liver Function Indicators
- Reduced Liver Injury
- Reduced Liver Injury Marker
- Reduced Need for Continuous Renal Replacement Therapy
- Reduced Organ Failure Severity
- Reduced Organ Injury
- Reduced Plasma Urea Level
- Reduced Short-term Mortality
- Reduced Urea Level
- Stabilized Total Bilirubin Levels