Best Supplements for Reduced Organ Dysfunction
Ranked by research evidence. Compare 1 supplement across 4 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Very low evidence4 studies
Across 4 studies, the evidence predominantly shows neutral or harmful effects of high-dose intravenous vitamin C on organ dysfunction, with only 1 study reporting a statistically significant harmful effect (small magnitude). The median study duration was 4 days, with most research focusing on critically ill patients (e.g., post-cardiac arrest, septic shock). The highest-quality trial (10 g/day IV for 4 days in comatose cardiac arrest survivors) found that vitamin C led to significantly worse organ function compared to placebo.
Dose: 10 g intravenous daily or 25 mg/kg every 6 h
1 supplement
- Very lowVitamin CAcross 4 studies, the evidence predominantly shows neutral or harmful effects of high-dose intravenous vitamin C on organ dysfunction, with only 1 study reporting a statistically significant harmful effect (small magnitude). The median study duration was 4 days, with most research focusing on critically ill patients (e.g., post-cardiac arrest, septic shock). The highest-quality trial (10 g/day IV for 4 days in comatose cardiac arrest survivors) found that vitamin C led to significantly worse organ function compared to placebo. · Dose: 10 g intravenous daily or 25 mg/kg every 6 h3 neutral1 harmful4 studies