Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis (ALS), also known as motor neurone disease (MND) or Lou Gehrig's disease, is a rare but terminal neurodegenerative disorder that leads to the progressive loss of upper and lower motor neurons, resulting in muscle stiffness, weakness, and ultimately complete paralysis, including the loss of the ability to eat, speak, move, and breathe. ALS has no cure and can also cause cognitive difficulties in about 50% of those affected.
Health Outcomes
- Activated Mitophagy Pathway
- Decreased Vastus Medialis Thickness
- Delayed Disease Progression
- Delayed Neurodegeneration
- Enhanced Autophagy
- Enhanced Neurological Disorder Management
- Enhanced Reactive Oxygen Species Resistance
- Enhanced Superoxide Dismutase Activity
- Facilitated Mitophagy
- Impaired Vacuolar Function
- Improved ALSFRS-R Score
- Improved Amyotrophic Lateral Sclerosis Outcome
- Improved Communication Skills
- Improved Force Production
- Improved Gait Speed
- Improved Glutathione Level
- Improved Gross Motor Function
- Improved Inspiratory Muscle Oxygenation
- Improved Leg Strength
- Improved Maximal Inspiratory Pressure
- Improved Maximal Voluntary Contraction
- Improved Maximal Voluntary Isometric Contraction
- Improved Maximal Voluntary Isometric Contraction Force
- Improved Motor Function
- Improved Motor Outcome
- Improved Motor Symptom
- Improved Muscle Composition
- Improved Muscle Function
- Improved Muscle Function Recovery
- Improved Muscle Integrity
- Improved Muscle Spasm
- Improved Neurodegenerative Disease Symptoms
- Improved Neurodegenerative Disorder
- Improved Neurological Health
- Improved Neurological Parameter
- Improved Neurological Symptoms
- Improved Neuromuscular Function
- Improved Neuromuscular Power
- Improved Neuromuscular Strength
- Improved Neuronal Survival
- Improved Neuroprotection
- Improved Power-Related Outcome
- Improved Quadriceps Contraction Strength
- Improved Reaching Ability
- Improved Serum Biochemical Catalase Levels
- Improved Skeletal Muscle Damage
- Improved Skeletal Muscle Function
- Improved Speech Function
- Improved Strength
- Improved Superoxide Dismutase Activity
- Improved Swallowing Function
- Improved Thigh Muscle pH Value
- Improved Upper Body Strength
- Improved Vertical Jump
- Increased Apoptosis
- Increased Autophagy
- Increased Cysteine Level
- Increased Myogenin Level
- Increased Neuronal Cell Survival
- Increased Oxidative Stress Tolerance
- Increased Serine Level
- Increased Superoxide Dismutase Activity
- Maintained Cytoskeletal Integrity
- Maintained Muscle Integrity
- Nervous System Dysfunction in Host
- Neuroprotection in Neurodegenerative Diseases
- No Significant Improvement in Locomotor Activity
- Preserved Wheel-Running Activity
- Prevention of Neurological Disorders
- Reduced 10-meter Walk Test Time
- Reduced 24-Hydroxycholesterol to Total Cholesterol Ratio
- Reduced Apoptosis Signal-Regulating Kinase 1 Level
- Reduced Brain Inflammation
- Reduced Choking Index
- Reduced Cytoskeleton Disruption
- Reduced Disease Progression
- Reduced Double Twitch Area Under the Curve
- Reduced Dysphagia
- Reduced Dysphagia Severity
- Reduced Dysphagia Symptom Score
- Reduced Ferroptosis
- Reduced Glial Cell Activation
- Reduced Glutamate Level
- Reduced Lean Mass
- Reduced Locomotor Impairment
- Reduced Motor Symptom
- Reduced Muscle Degeneration
- Reduced Muscle Symptom
- Reduced Muscle Thickness
- Reduced Muscle Wasting
- Reduced Muscle Weakness
- Reduced N-acetylaspartate Level
- Reduced Neurodegeneration Symptoms
- Reduced Neurodegenerative Disease-Related Dysfunction
- Reduced Neuroinflammation
- Reduced Neuroinflammatory Markers
- Reduced Neurological Symptoms
- Reduced Neuronal Death
- Reduced Neurotoxicity
- Reduced Nuclear Factor Kappa-B Level
- Reduced Oxidized Glutathione Level
- Reduced Peak Inspiratory Pressure
- Reduced Protein Damage
- Reduced Proteotoxicity
- Reduced Quadriceps Muscle Cross-Sectional Area
- Reduced Serum Glutamate Levels
- Reduced Swimming Time
- Reduced Vascular Endothelial Growth Factor Level
- Reduced Weakness
- Regulated Microglial Activation
- Restored Neurodegeneration-Associated Metabolic Alterations
- Slowed Disease Progression
- Slowed Neuronal Damage Progression
- Stabilized Disease Progression
- Stabilized Neurofilament Light Chain Level
- Worsened Motor Function
- Worsened Pyramidal Score