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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Best Supplements for Improved Bone Mineral Density

Ranked by research evidence. Compare 5 supplements across 10 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.

Top picks by evidence

  • Low evidence4 studies

    Across 4 studies, 1 reported a small beneficial effect of combined calcium and vitamin D supplementation on bone mineral density (BMD) in postmenopausal women with osteoporosis, while 3 studies showed neutral effects. The beneficial finding was statistically significant (p=0.01) in a meta-analysis of 869 participants. The median study duration was 297 days, and most studies enrolled clinical populations (postmenopausal women or kidney transplant recipients).

    Product match
    Viva NaturalsVitamin D3 with Organic Liquid Coconut Oil
    125 mcg · $15.16 · ★5.0 (208)
  • Low evidence3 studies

    Across 3 studies, 1 reported a small beneficial effect of calcium supplementation on bone mineral density, while 2 found neutral effects. The beneficial finding is from a meta-analysis in postmenopausal women with osteoporosis; the neutral studies involved kidney transplant recipients and postmenopausal women with type 2 diabetes. The median study duration was 504 days (from 1 study). Overall evidence is mixed and preliminary.

    Product match
    SolgarEster-C Plus
    108 mg · $27.74 · ★5.0 (70)
5 supplements
  • LowVitamin DAcross 4 studies, 1 reported a small beneficial effect of combined calcium and vitamin D supplementation on bone mineral density (BMD) in postmenopausal women with osteoporosis, while 3 studies showed neutral effects. The beneficial finding was statistically significant (p=0.01) in a meta-analysis of 869 participants. The median study duration was 297 days, and most studies enrolled clinical populations (postmenopausal women or kidney transplant recipients).1 beneficial3 neutral4 studies
  • LowCalciumAcross 3 studies, 1 reported a small beneficial effect of calcium supplementation on bone mineral density, while 2 found neutral effects. The beneficial finding is from a meta-analysis in postmenopausal women with osteoporosis; the neutral studies involved kidney transplant recipients and postmenopausal women with type 2 diabetes. The median study duration was 504 days (from 1 study). Overall evidence is mixed and preliminary.1 beneficial2 neutral3 studies
  • Casein Protein1 beneficial1 study
  • Soy Protein1 beneficial1 study
  • Whey Protein1 beneficial1 study
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