Best Supplements for Improved Left Ventricular Ejection Fraction
Ranked by research evidence. Compare 7 supplements across 10 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Very low evidence3 studies
Across 3 studies, 1 reported a beneficial small-sized effect on left ventricular ejection fraction, while 2 found neutral effects. The beneficial finding came from a systematic review of 1755 patients with heart failure using a multi-ingredient supplement including thiamine, though the specific effect of vitamin B1 alone was not isolated. Studies primarily used doses of 50-100 mg/day in clinical populations, with a median duration of only 15 days, which is likely insufficient to assess cardiac remodeling effects.
Dose: 50-100 mg/day
7 supplements
- Very lowVitamin B1Across 3 studies, 1 reported a beneficial small-sized effect on left ventricular ejection fraction, while 2 found neutral effects. The beneficial finding came from a systematic review of 1755 patients with heart failure using a multi-ingredient supplement including thiamine, though the specific effect of vitamin B1 alone was not isolated. Studies primarily used doses of 50-100 mg/day in clinical populations, with a median duration of only 15 days, which is likely insufficient to assess cardiac remodeling effects. · Dose: 50-100 mg/day1 beneficial2 neutral3 studies