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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Best Supplements for Improved Left Ventricular Ejection Fraction

Ranked by research evidence. Compare 5 supplements across 8 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.

Top picks by evidence

  • Very low evidence3 studies

    Across 3 studies, 1 reported a beneficial small effect of Vitamin B1 (as part of a multi-nutrient supplement) on left ventricular ejection fraction, while 2 studies found no significant effect (neutral). The most-studied dose was 50–100 mg/day in clinical populations with heart conditions or undergoing cardiac surgery. The median study duration was short (15 days), so longer-term effects remain unclear. Evidence is small and preliminary.

    Dose: 50–100 mg/day
    Product match
    Bluebonnet NutritionMen's ONE
    1.2 mg · $14.80 · ★5.0 (21)
5 supplements
  • L-Carnitine2 beneficial2 studies
  • Very lowVitamin B1Across 3 studies, 1 reported a beneficial small effect of Vitamin B1 (as part of a multi-nutrient supplement) on left ventricular ejection fraction, while 2 studies found no significant effect (neutral). The most-studied dose was 50–100 mg/day in clinical populations with heart conditions or undergoing cardiac surgery. The median study duration was short (15 days), so longer-term effects remain unclear. Evidence is small and preliminary. · Dose: 50–100 mg/day1 beneficial2 neutral3 studies
  • L-Arginine1 beneficial1 study
  • rice bran1 beneficial1 study
  • Vitamin C1 neutral1 study
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