Vitamin B1 and Improved Left Ventricular Ejection Fraction

• Impact of thiamin supplementation on thiamin pyrophosphate effect and cardiac function in pediatric heart disease patients on diuretics: a randomized controlled trial.

  • 2026-03-23
  • RCT · n = 45
  • Scientific reports 16(1)
  • • Rathaporn Sumboonnanonda
    • Chodchanok Vijarnsorn
    • Puthita Saengpanit
    • Chatchawan Srisawat
    • Kwanjai Chotipanang
    • Sarawut Junnu
    • Supawan Kunnangja
    • Hathaichanok Rukprayoon
    • Phakkanan Phuangphan
    • Bordeesuda Suiwongsa
    • Sompong Liammongkolkul
    • Phakwan Laohathai
    • Narumon Densupsoontorn

  • PubMed: 41872295
  • DOI: 10.1038/s41598-026-45100-4

  2 Insights on

  • Improved Left Ventricular Ejection Fraction

  • High evidence
  • Rigorous Journal
  • Clinical

  After 4 weeks, no significant differences in changes in ... LVEF (p = 0.441) were observed among the three groups.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  50 mg/day

• Effect of Combined Vitamin C and Thiamine Therapy on Myocardial and Inflammatory Markers in Cardiac Surgery: A Randomized Controlled Clinical Trial.

  • 2025-03-13
  • RCT · n = 64
  • Nutrients 17(6)
  • • Mantana Saetang
    • Wirat Wasinwong
    • Maliwan Oofuvong
    • Jutarat Tanasansutthiporn
    • Laortip Rattanapittayaporn
    • Sutthasinee Petsakul
    • Pongsanae Duangpakdee
    • Puripong Rodneam
    • Parin Boonthum
    • Supphamongkhon Khunakanan
    • Chaitong Churuangsuk
    • Wilaiwan Sriwimol
    • Amphan Chantarokon
    • Kanjana Nuanjun
    • Dararat Yongsata

  • PubMed: 40290059
  • DOI: 10.3390/nu17061006

  7 Insights on

  • Improved Left Ventricular Ejection Fraction

  • High evidence
  • Rigorous Journal
  • Clinical

  no significant differences in hemodynamic stability or left ventricular ejection were observed between the groups

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  100 mg