Best Supplements for Improved Mental Health
Ranked by research evidence. Compare 18 supplements across 24 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Low evidence3 studies
Across all 3 studies (all reviews), a small beneficial effect of Lactobacillus helveticus Rosell-52 on improved mental health was reported. No studies reported neutral or harmful findings, and none reported statistically significant results. The evidence base is small, and effect sizes were consistently small. No specific dose range, form, or study duration was reported, and populations were general adult humans.
- Very low evidence3 studies
Across 3 review articles, all reported beneficial but small-sized effects of Bifidobacterium bifidum Rosell-71 on mental health outcomes. No consistent dose, form, or duration data were reported, and no study reported statistically significant results. The evidence is derived entirely from secondary analyses, not direct trials.
- LowLactobacillus helveticus Rosell-52Across all 3 studies (all reviews), a small beneficial effect of Lactobacillus helveticus Rosell-52 on improved mental health was reported. No studies reported neutral or harmful findings, and none reported statistically significant results. The evidence base is small, and effect sizes were consistently small. No specific dose range, form, or study duration was reported, and populations were general adult humans.3 beneficial3 studies
- Very lowBifidobacterium bifidum Rosell-71Across 3 review articles, all reported beneficial but small-sized effects of Bifidobacterium bifidum Rosell-71 on mental health outcomes. No consistent dose, form, or duration data were reported, and no study reported statistically significant results. The evidence is derived entirely from secondary analyses, not direct trials.3 beneficial3 studies