Best Supplements for Improved Mental Health
Ranked by research evidence. Compare 19 supplements across 25 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Very low evidence3 studies
Across 3 studies (all reviews from 2022–2025), all reported small beneficial effects of Lactobacillus helveticus Rosell-52 on mental health outcomes. However, none of the included studies provided statistical significance testing for this specific supplement-outcome pair, and no consistent dose, form, or duration data were extractable. The evidence base is very small and entirely review-level, making the aggregate finding preliminary.
- Very low evidence3 studies
Across all 3 available studies, beneficial but small effects of Bifidobacterium bifidum Rosell-71 on mental health were reported, though none reached statistical significance. The evidence base is limited to review articles rather than direct interventional trials, and no specific dose, form, or study duration was consistently reported.
- Very lowLactobacillus helveticus Rosell-52Across 3 studies (all reviews from 2022–2025), all reported small beneficial effects of Lactobacillus helveticus Rosell-52 on mental health outcomes. However, none of the included studies provided statistical significance testing for this specific supplement-outcome pair, and no consistent dose, form, or duration data were extractable. The evidence base is very small and entirely review-level, making the aggregate finding preliminary.3 beneficial3 studies
- Very lowBifidobacterium bifidum Rosell-71Across all 3 available studies, beneficial but small effects of Bifidobacterium bifidum Rosell-71 on mental health were reported, though none reached statistical significance. The evidence base is limited to review articles rather than direct interventional trials, and no specific dose, form, or study duration was consistently reported.3 beneficial3 studies