Best Supplements for Increased Helicobacter pylori Eradication Rate
Ranked by research evidence. Compare 17 supplements across 20 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- High evidence4 studies
The evidence from 4 studies (3 beneficial, 1 neutral) indicates that adjunctive Saccharomyces boulardii supplementation yields a small increase in Helicobacter pylori eradication rates compared to standard therapy alone. The most supportive data come from a large meta-analysis of 11 RCTs (n=2,295), which found a 12% relative improvement (RR=1.12; 95% CI: 1.06-1.18). Doses and treatment duration varied, with the median study duration being approximately 27 days. The evidence is strongest for concurrent use with bismuth quadruple or triple therapy.
17 supplements
- Highsaccharomyces boulardiiThe evidence from 4 studies (3 beneficial, 1 neutral) indicates that adjunctive Saccharomyces boulardii supplementation yields a small increase in Helicobacter pylori eradication rates compared to standard therapy alone. The most supportive data come from a large meta-analysis of 11 RCTs (n=2,295), which found a 12% relative improvement (RR=1.12; 95% CI: 1.06-1.18). Doses and treatment duration varied, with the median study duration being approximately 27 days. The evidence is strongest for concurrent use with bismuth quadruple or triple therapy.3 beneficial1 neutral4 studies