Best Supplements for Increased Helicobacter pylori Eradication Rate
Ranked by research evidence. Compare 17 supplements across 22 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Moderate evidence5 studies
Across 5 studies, 4 reported beneficial effects of Saccharomyces boulardii on increasing Helicobacter pylori eradication rates, with the predominant effect size being small to moderate. The highest-quality evidence comes from a 2025 meta-analysis of 11 RCTs (n = 2,295) showing a statistically significant 12% relative improvement in eradication rates (RR = 1.12; 95% CI: 1.06-1.18, p < 0.01) with adjunctive S. boulardii. No single dose or form was consistently reported, and the median study duration was 14 days (range 10–44 days) across the 3 studies reporting duration.
17 supplements
- Moderatesaccharomyces boulardiiAcross 5 studies, 4 reported beneficial effects of Saccharomyces boulardii on increasing Helicobacter pylori eradication rates, with the predominant effect size being small to moderate. The highest-quality evidence comes from a 2025 meta-analysis of 11 RCTs (n = 2,295) showing a statistically significant 12% relative improvement in eradication rates (RR = 1.12; 95% CI: 1.06-1.18, p < 0.01) with adjunctive S. boulardii. No single dose or form was consistently reported, and the median study duration was 14 days (range 10–44 days) across the 3 studies reporting duration.4 beneficial1 neutral5 studies