Best Supplements for Reduced Crying Duration
Ranked by research evidence. Compare 11 supplements across 13 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Low evidence3 studies
Across 3 studies, 2 reported beneficial effects on reduced crying duration, with 1 large effect (systematic review of 2,242 infants with colic, WMD -51.3 h [CI95% -72.2 to -30.5 h], p=0.0001) and 1 small significant effect (review of breastfed infants). The remaining study (RCT, n=89 neonates on antibiotics) found no statistically significant benefit. The median study duration was 42 days. The predominant effect direction is beneficial, but effect sizes are mixed (small to large). Most evidence pertains to infants with colic.
Product matchBioGaia — Kids, Immune Active with L. Reuteri + Vitamin D, Orange· $26.99 · ★4.8 (510)
11 supplements
- LowLactobacillus reuteri DSM 17938Across 3 studies, 2 reported beneficial effects on reduced crying duration, with 1 large effect (systematic review of 2,242 infants with colic, WMD -51.3 h [CI95% -72.2 to -30.5 h], p=0.0001) and 1 small significant effect (review of breastfed infants). The remaining study (RCT, n=89 neonates on antibiotics) found no statistically significant benefit. The median study duration was 42 days. The predominant effect direction is beneficial, but effect sizes are mixed (small to large). Most evidence pertains to infants with colic.2 beneficial1 neutral3 studies